O-sialoglycoprotein endopeptidase (, glycoprotease, glycophorin A proteinase, glycoproteinase, sialoglycoprotease, sialoglycoproteinase, "OSGE") is an enzyme. This enzyme catalyses the following chemical reaction
Hydrolysis of O-sialoglycoproteins; cleaves -Arg31-Asp- bond in glycophorin A. Does not cleave unglycosylated proteins, desialylated glycoproteins or glycoproteins that are only N-glycosylated
This enzyme is secreted by the bacterium Pasteurella haemolytica.
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