Leucolysin (, Leucostoma neutral proteinase, Leucostoma peptidase A) is an enzyme. This enzyme catalyses the following chemical reaction
Cleavage of Phe1-Val, His5-Leu, Ala14-Leu, Gly20-Glu, Gly23-Phe and Phe24-Phe bonds in insulin B chain as well as N-blocked dipeptides
This enzyme is isolated from the venom of the western cottonmouth moccasin snake (Agkistrodon piscivorus leucostoma).
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