The 1979–80 Macedonian Republic League was the 36th since its establishment. FK Rabotnichki won their 10th and last championship title.
Participating teams Club City 11 Oktomvri Prilep Belasica Strumica Borec Titov Veles Bregalnica Shtip Karaorman Struga Kozhuf Gevgelija Ljuboten Tetovo Napredok Kichevo Pelister Bitola Pobeda Valandovo Rabotnichki Skopje Sasa Makedonska Kamenica Sloga Skopje Tikvesh Kavadarci Vardar Negotino Vardarski Bogdanci
Final table
External links SportSport.ba Football Federation of Macedonia