William Talley House is a historic home located in Brandywine Hundred, unincorporated New Castle County, Delaware, - Compare with the postal address. with a Wilmington postal address. - The postal city is "Wilmington" but the property is outside of the Wilmington city limits. It was built about 1770, as a one-room deep, two-room wide fieldstone dwelling. The house has evolved to a -story, four-bay, rectangular dwelling with a steep gable roof.

It has two rectangular inside end brick chimneys covered with stucco that project through the gable peak.

The shed-roofed, sun porch addition was built in the 1940s and a saltbox form rear frame addition was built in the 1960s. and

It was added to the National Register of Historic Places in 1985.

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