Salerno is a surname. Notable people with the surname include:
Adriana Salerno (born 1979), Venezuelan-American mathematician Anthony Salerno (1911–1992), Italian-American mobster Enrico Maria Salerno (1926–1994), Italian actor Fabio Salerno (born 1979), Italian Catholic priest and second secretary to the Pope Francesco Carmelo Salerno (1925–1998), Member of the Italian parliament and Football Club Manager Jessica Salerno, American psychologist Joe Salerno (born 1981), American basketball coach José Salerno (1914–1984), Argentine football player and manager Joseph P. Salerno (1914–1981), American architect Joseph T. Salerno (born 1950), Austrian School economist José Luis Salerno, Argentine crime suspect Nicola Salerno (1910–1969), Italian lyricist Nicola Salerno (sporting executive) (1956–2026), Italian football sporting director Ralph Salerno (1925-2003), New York police officer, author and recognized expert on the American mafia Randy Salerno (1963–2008), American news anchor Sabrina Salerno (born 1968), Italian singer, showgirl, model, actress and record producer Shane Salerno (born 1972), American screenwriter and producer