Ghent is a surname. Notable people with the surname include:

Emma Ghent Curtis (1860–1918), American novelist, poet, newspaper publisher, Populist, and suffragist Emmanuel Ghent (1925–2003), Canadian composer and psychoanalyst Matthew Ghent (born 1980), English footballer Ronnie Ghent (born 1980), American football player and coach W. J. Ghent (1866–1942), American writer