Ghilardi () is an Italian surname. Notable people with the surname include:
Alberto Ghilardi (1909–1971), Italian cyclist Aline Ghilardi (born 1986), Brazilian biologist and palaeontologist Daniele Ghilardi (born 2003), Italian footballer Luigi Ghilardi (1805–1864), Italian general Rebecca Ghilardi (born 1999), Italian pair skater
See also Gilardi Ghirardi Ghilardotti Ghilarducci