Fontanelli is an Italian surname. Notable people with the surname include:
Achille Fontanelli (1775–1838), Italian nationalist and Napoleonic general Alfonso Fontanelli (1557–1622), Italian composer Cristina Fontanelli, American actress and opera singer Fabiano Fontanelli (born 1965), Italian cyclist Giuseppe Fontanelli, known as Bissietta (1910–1977), Italian painter in Australia