Dipeptidase E (, aspartyl dipeptidase, peptidase E, PepE gene product (Salmonella typhimurium)) is an enzyme. This enzyme catalyses the following chemical reaction
Dipeptidase E catalyses the hydrolysis of dipeptides Asp!Xaa. It does not act on peptides with N-terminal Glu, Asn or Gln, nor does it cleave isoaspartyl peptides
A free carboxy group is not absolutely required in the substrate.
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