Clostridial aminopeptidase (, Clostridium histolyticum aminopeptidase) is an enzyme. This enzyme catalyses the following chemical reaction

Release of any N-terminal amino acid, including proline and hydroxyproline, but no cleavage of Xaa-Pro-

This enzyme is secreted enzyme from Clostridium histolyticum. It requiring Mn2+ or Co2+.

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