UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolysing)

UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolysing) (, UDP-Bac2Ac4Ac 2-epimerase, NeuC) is an enzyme with systematic name UDP-N,N'-diacetylbacillosamine hydrolase (2-epimerising). It catalyses the following chemical reaction

The enzyme characterised from Legionella pneumophila and Campylobacter species removes the glycoside unit from uridine diphosphate N,N'-diacetylbacillosamine to give uridine diphosphate and 2,4-diacetamido-2,4,6-trideoxy-α-D-mannopyranose (1), with inversion of the stereochemistry at the 2-position.

This enzyme requires magnesium as Mg2+. It is involved in biosynthesis of legionaminic acid.

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