Baicalin-beta-D-glucuronidase (, baicalinase) is an enzyme with systematic name 5,6,7-trihydroxyflavone-7-O-beta-D-glucupyranosiduronate glucuronosylhydrolase. It catalyses the following chemical reaction
The enzyme characterised from Scutellaria species removes the glycoside unit from baicalin, to give the flavone baicalein and D-glucuronic acid.
The enzyme also hydrolyses wogonin 7-O-beta-D-glucuronide and oroxylin 7-O-beta-D-glucuronide with lower efficiency.
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