Frankfurter is a surname. Notable people with the surname include:

David Frankfurter (1909–1982), Croatian–Israeli assassin of Nazi leader Wilhelm Gustloff Felix Frankfurter (1882–1965), Associate Justice of the United States Supreme Court Mavro Frankfurter (1875–1942), Croatian and Vinkovci rabbi Philipp Frankfurter (c. 1450 – 1511), Viennese writer