Sucrose α-glucosidase (, sucrose α-glucohydrolase, sucrase, sucrase-isomaltase, sucrose.α.-glucohydrolase, intestinal sucrase, sucrase(invertase)) is an enzyme with systematic name sucrose-α-D-glucohydrolase. It catalyses the hydrolysis of sucrose and maltose by an α-D-glucosidase-type action.
For example, sucrose is hydolysed to fructose and glucose (shown in their aldehydo forms):
This enzyme is isolated from intestinal mucosa as a single polypeptide chain. The human sucrase-isomaltase is a dual-function enzyme with two GH31 domains, one serving as the isomaltase, the other serving as a sucrose α-glucosidase.
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