D-glycero-β-D-manno-heptose 1,7-bisphosphate 7-phosphatase (EC 3.1.3.82) is an enzyme with systematic name D-glycero-β-D-manno-heptose 1,7-bisphosphate 7-phosphohydrolase. It catalyses the following chemical reaction
The enzyme characterised from Escherichia coli hydrolyses D-glycero-β-D-manno-heptose 1,7-bisphosphate to D-glycero-β-D-manno-heptose 1-phosphate and orthophosphate (Pi). The structure of the enzyme from Burkholderia thailandensis has been determined by X-ray crystallography.
The product is acted on by the enzyme D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase to give the adenosine diphosphate (ADP) derivative, ADP-L-glycero-β-D-manno-heptose.
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