Entwistle is an English surname. Notable people with the surname include:
Alan Entwistle (1949–1996), British scholar of Hindi Antony Beauchamp Entwistle (1918–1957), British photographer Bobby Entwistle (1938–2000), English footballer Cyril Entwistle (1887–1974), British politician Darren Entwistle (b. 1962), Canadian businessman David Entwistle (b. 1964), United States Virgin Islands Olympic bobsledder Edward Entwistle (1815–1909), English railroad engineer Ernest Entwistle Cheesman (1898–1983), English botanist George Entwistle (b. 1962), British television producer Harold Entwistle, English-born American actor and theatre director Harry Entwistle (b. 1940), English-born Australian priest Ian Entwistle (b. 1986), English mixed martial artist James F. Entwistle (b. 1956), American diplomat John Entwistle (1944–2002), the original bass guitarist of The Who John Entwistle (cyclist) (1932–2013), British cyclist Jonty Entwistle (1868–unknown), English footballer Kirith Entwistle (born 1991), British politician Louisa Entwistle (born 1887), English suffragette MacKenzie Entwistle (b. 1999), Canadian ice hockey player Neil Entwistle (b. 1978), convicted of the 2006 murder of his wife and daughter Noel Entwistle (b. 1936), UK educational psychologist Peg Entwistle (1908–1932), British actress Ralph Entwistle (c. 1805–1830), English-Australian bushranger Robert Entwistle (1941–2019), English cricketer Vicky Entwistle (b. 1968), British actress Wayne Entwistle (b; 1958), English footballer
See also Entwisle, a related surname Entwistle, a village in Lancashire