APICA or Apica may refer to:
Toponyms Apica River, stream in Charlevoix Regional County Municipality, Capitale-Nationale, Quebec, Canada Mont-Apica, Quebec, unorganized territory in Lac-Saint-Jean-Est Regional County Municipality, Saguenay–Lac-Saint-Jean, Quebec, Canada RCAF Station Mont Apica, a radar station Mont-Apica, Quebec
Chemistry 1-Amino-5-phosphonoindan-1-carboxylic acid, also known as APICA APICA (synthetic cannabinoid drug) (N-(1-adamantyl)-1-pentyl-1H-indole-3-carboxamide))