Giovanni Colonna or John Colonna may refer to:
Giovanni Colonna (died 1245) (1170–1245), cardinal of the Roman Catholic Church Giovanni Colonna (archbishop) (1205–1263), archbishop of Messina, nephew of the cardinal Giovanni Colonna (historian) (1298–1343/44), Dominican and writer, friend of Petrarch Giovanni Colonna (cardinal, 1295–1348) (1295–1348), Roman Catholic cardinal Giovanni Colonna (cardinal, 1456–1508) (1456–1508), Roman Catholic cardinal Giovanni Paolo Colonna (c. 1637–1695), Italian musician and composer Giovanni Colonna (archaeologist) (born 1934), Italian scholar of ancient Italy John Colonna (born 1962), Puerto Rican child who disappeared along with his sister Gianinna