(d)CMP kinase (, prokaryotic cytidylate kinase, deoxycytidylate kinase, dCMP kinase, deoxycytidine monophosphokinase) is an enzyme with systematic name ATP:(d)CMP phosphotransferase. It catalyses two related chemical reactions. The first converts the nucleotide, cytidine monophosphate (CMP), to cytidine diphosphate by transferring a phosphate group from the cofactor, adenosine triphosphate (ATP), which is converted to adenosine diphosphate (ADP):

Alternatively, the enzyme can act on deoxycytidine monophosphate (dCMP):

This prokaryotic enzyme is specific for CMP or dCMP.

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