Blackburne is a surname. Notable people with the surname include:
Anna Blackburne (1726–1793), English botanist Anna Blackburne-Rigsby (born Anna Blackburne, 1961), American judge Francis Blackburne (1782–1867), Lord Chancellor of Ireland Harry Blackburne DSO, MC (1878–1963), an Anglican clergyman John Blackburne (botanist) (1694–1786), English businessman and botanist, father of Anna John Ireland Blackburne (1783–1874), MP for Newton (1807–1818) and Warrington (1835–1847) John Ireland Blackburne (1817–1893), MP for South West Lancashire 1875–1885 Joseph Henry Blackburne (1841–1921), British chess master Lancelot Blackburne (1658–1743), English clergyman, Archbishop of York, purported pirate Lena Blackburne (1886–1968), American Major League baseball player and manager