Ceccherini () is an Italian surname derived from the male given name Cecco. Notable people with the surname include:
Andrea Ceccherini (born 1974), Italian civic leader Federico Ceccherini (born 1992), Italian footballer Giuseppe Ceccherini (1829–1899), Italian composer Massimo Ceccherini (born 1965), Italian actor, comedian and film director Sante Ceccherini (1863–1932), Italian fencer Silvano Ceccherini (1915–1974), Italian anarchist and writer Tito Ceccherini (born 1973), Italian orchestra conductor
See also Ceccarini