Crispin is a surname. Notable people with the surname include:

Ann C. Crispin (1950–2013), American science fiction writer Edmund Crispin (1921–1978), pseudonym of Robert Bruce Montgomery, an English crime writer Gilbert Crispin (c. 1055 – 1117), Christian author and Anglo-Norman monk Jessa Crispin (born 1978), editor-in-chief of Bookslut, a litblog and webzine Joe Crispin (born 1979), American professional basketball player Jon Crispin (born 1981), American collegiate basketball player Mark Crispin (born 1956), inventor of the IMAP protocol

See also Crespin (surname), people with this surname