Mayfield is an English surname. Notable people with the surname include:
Baker Mayfield (born 1995), American football player Brandon Mayfield (born 1966), American Muslim man erroneously linked to the 2004 Madrid train bombings Cleo Mayfield (1898–1954), American actress and singer Curtis Mayfield (1942–1999), American soul, R&B, and funk singer Debbie Mayfield (born 1956), American politician from Florida Earle B. Mayfield (1881–1964), American politician from Texas Edwin Mayfield (1870–1961), British international rugby union player Harold F. Mayfield (1911–2007), American business executive and ornithologist Irvin Mayfield (born 1977), American jazz musician, New Orleans J. C. Mayfield (born c. 1856), American businessman J. J. Mayfield (1861–1927), American judge, politician and educator from Alabama Jack Mayfield (born 1990), American baseball player Jalen Mayfield (born 2000), American football player James J. Mayfield (1911–1956), Alabama lawyer and judge Jeremy Mayfield (born 1969), American auto racer Jessica Lea Mayfield (born 1989), American singer-songwriter Julian Mayfield (1928–1984), American actor, director, writer, lecturer and civil rights activist Julie Mayfield (born 1967), American politician from North Carolina Katherine Mayfield (born 1958), American writer Maryhelen Mayfield (1946—2024), American ballet dancer and arts administrator Matthew Mayfield (born 1983), American singer-songwriter Max Mayfield (born 1948), American meteorologist Melvin Mayfield (1919-1990), American corporal and Medal of Honor recipient Percy Mayfield (1920–1984), American songwriter and singer Scott Mayfield (born 1992), American ice hockey player for the New York Islanders Scottie Mayfield (born 1950 or 1951), president of Mayfield Dairy Stan Mayfield (1955–2008), American politician from Florida Virginia Henry Mayfield (1889–1944), first female judge in Alabama