Deppe is a surname. Notable people with the surname include:
Dale Deppe, American horticulturalist Ferdinand Deppe (1794–1861), German naturalist, explorer and painter Hans Deppe (1897–1969), German actor and film director Jaro Deppe (born 1948), German footballer Ludwig Deppe (1828–1890), German composer, conductor and piano teacher Paula Deppe (1886–1922), Bohemian-German painter, engraver and illustrator Royce Deppe (born 1965), South African tennis player Ted Deppe, American poet Ulrike Deppe (born 1953), German slalom canoeist
See also Depper