Eupithecia guayacanae is a moth in the family Geometridae. It is found the Region of Santiago (Santiago Province) in Chile., 1991: The Eupithecia (Lepidoptera, Geometridae) of Chile. 2. American Museum Novitates 3020: 1-14. Full article: . The habitat consists of the Central Valley Biotic Province.

The length of the forewings is about 10 mm for males.

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