Gilis or Ģīlis is a surname. Notable people with the surname include:
Jānis Gilis (1943–2000), Latvian footballer Antoine Gilis (1702–1781), French musician and composer Valdis Ģīlis (born 1954), Latvian politician
See also Gillis (disambiguation) Gillis (surname) McGillis Gilles (surname) Gillies Gilliss