Ernest Sykes may refer to:
Ernest Sykes (VC) (1885–1949), English recipient of the Victoria Cross Ernest Ruthven Sykes (1867–1954), British malacologist Ernest Sykes (cricketer) (1869–1925), English cricketer Ernie Sykes (1915–1997), English footballer Ernest Eugene Sykes (1867–1942), New Orleans businessman and Freemason