Jakupović () is a Bosnian surname. Notable people with the surname include:
Arnel Jakupović (born 1998), Austrian footballer Dalila Jakupović (born 1991), Slovenian tennis player of Bosnian descent Ajdin Jakupović (born 1990), Swedish-Bosnian entrepreneur Eldin Jakupović (born 1984), Swiss-Bosnian footballer Alexandros Jakupovic (born 1981), Greek former tennis player of Greek and Bosnian descent