RS1 or RS-1 may refer to: ALCO RS-1, a 4-axle diesel-electric locomotive built by Alco-GE and later by Alco alone K-5 (missile), also known as RS-1U or product ShM, an early Soviet air-to-air missile The Reid and Sigrist R.S.1, a British twin-engined, three-seat advanced trainer developed during World War II Retinoschisin, a protein that in humans is encoded by the RS1 gene Ross RS-1 Zanonia, a single seat, gull-winged glider Rohini Satellite 1, an Indian satellite in the Rohini satellite series (7080) 1986 RS1, generally written as (7080) 1986 RS1, a main-belt minor planet Sikorsky S-41, an amphibious flying boat airliner designated by the U.S. Navy as RS-1 Stadler Regio-Shuttle RS1, a diesel railcar manufactured by Stadler Rail AG Goodyear RS-1 America's first semi-rigid airship RS/1, statistical software from Bolt, Beranek and Newman The first Randall–Sundrum model Long Wall RS1, a liquid-fuelled small-lift launch vehicle RS1, a type of resistant starch