Calthorpe is a surname. Notable people with the surname include:

Anne Calthorpe (died c.1579), Countess of Sussex Sir Charles Calthorpe (c. 1540–1616), English-born judge in Elizabethan and early Jacobean Ireland David Calthorpe (born 1973), former Australian rules footballer Freddie Calthorpe (1892–1935), English cricketer James Calthorpe of Cockthorpe (c. 1558–1615), Sheriff of Norfolk in 1614 James Calthorpe (Yeoman of the Removing Wardrobe) (1699–1784), English politician and courtier Sir Henry Calthorpe (1586–1637), English lawyer Sir Henry Calthorpe (died 1788) of Elvetham in Hampshire, a Knight of the Bath and a Member of Parliament for Hindon Isabella Calthorpe, stage name of Isabella Anstruther-Gough-Calthorpe (born 1980), English actress and model Sir James Calthorpe of East Barsham (1604–1652), Sheriff of Norfolk in 1643 Sir James Calthorpe (Roundhead) (died 1658), Sheriff of Suffolk, knighted by the Lord Protector Oliver Cromwell Mena Calthorpe (1905–1996), Australian writer Peter Calthorpe (born 1949)], architect and urban designer and planner Reynolds Calthorpe (1655–1719) of Elvetham in Hampshire, Member of Parliament for Hindon Reynolds Calthorpe, the younger (1689–1714), Member of Parliament for Hindon William Calthorpe (1410–1498), English aristocrat and Knight of the Bath Gough-Calthorpe family associated with the British title Baron Calthorpe: Henry Gough-Calthorpe, 1st Baron Calthorpe (1749–1798), 2nd Baronet Frederick Henry William Gough-Calthorpe, 5th Baron Calthorpe (1826–1893) Augustus Gough-Calthorpe, 6th Baron Calthorpe (1829–1910) Somerset Gough-Calthorpe, 7th Baron Calthorpe (1831–1912) Somerset Gough-Calthorpe (1864–1937), English admiral of the fleet Freddie Calthorpe (1892–1935), English cricketer