Drayton is a surname. Notable people with the surname include:
Academia Harold Drayton (1929–2018), Guyanese academic Richard Drayton (born 1964), Guyana-born historian
Military Percival Drayton (1812–1865), United States Navy officer, son of US Representative William Drayton of South Carolina Thomas Drayton (1809–1899), Confederate States Army general, son of US Representative William Drayton of South Carolina
Performing arts Charley Drayton (born 1965), American drummer, multi-instrumentalist, and producer – grandson of jazz bassist Charlie Drayton Charlie Drayton (1919–1953), American jazz bassist Clay Drayton (born 1947), American songwriter and record producer Paul Drayton (composer), English musician Poppy Drayton (born 1991), English actress Flavor Flav (born William J. Drayton in 1959), American rap artist
Public service and law J. Coleman Drayton (1852–1934), American lawyer and socialite, first husband of Charlotte Augusta Astor John Drayton (1766–1822), American politician, governor of South Carolina Joy Drayton (1916–2012), New Zealand teacher and politician William Drayton (1776–1846), American politician, US Representative from South Carolina William Henry Drayton (1742–1779), American lawyer, South Carolina delegate to Continental Congress William Drayton Sr. (1733–1790), American lawyer and judge
Sports Jerome Drayton (1945–2025), Canadian long-distance runner Maurice Drayton (born 1976), American football coach Paul Drayton (athlete) (1939–2010), American athlete, gold medal winner at the 1964 Summer Olympics
Other professions Bill Drayton (born 1943), American social entrepreneur and environmentalist Dean Drayton (born 1941), Australian church leader Michael Drayton (1563–1631), English poet