Brotherton is a surname. Notable people with the surname include:
Alice Williams Brotherton (1848–1930), American writer Edward Brotherton, 1st Baron Brotherton (1856–1930), English businessman and politician Helen Brotherton (vegetarian), English vegetarianism activist and philanthropist Helen Brotherton (1914–2009), English conservationist John Brotherton, American actor John Brotherton (industrialist) (1829–1917), innovative tube manufacturer who served as the 33rd Mayor of Wolverhampton 1883/84 Joseph Brotherton (1783–1857), English politician, minister and activist Martha Brotherton (1782–1861), English cookbook writer Michael Brotherton (born 1931), British journalist and politician Michael Brotherton (priest) (1935–2025), English Anglican priest Mike Brotherton (born 1968), American science fiction writer and astronomer Simon Brotherton, British sports announcer Thomas William Brotherton (1782–1868), British Army general Thomas of Brotherton, 1st Earl of Norfolk (1300–1338) Wilbur Brotherton (1922–2021), American politician