Wanyonyi is a surname of Kenyan origin. Notable people with the surname include:
Emmanuel Wanyonyi (born 2004), Kenyan middle-distance runner Jehovah Wanyonyi (1924–2015), Kenyan self-proclaimed god Tim Wanyonyi (born 1963), Kenyan lawyer and politician Cimberly Wanyonyi (born 2005), Swedish singer