José Luis Rodríguez may refer to:
First surname José Luis Rodríguez Aguilar (born 1994), Chilean cyclist José Luis Rodríguez Bebanz (born 1997), Uruguayan footballer José Luis Rodríguez Francis (born 1998), Panamanian footballer José Luis Rodríguez García (born 1946), Cuban politician José Luis Rodríguez Jiménez (born 1961), Spanish historian José Luis Rodríguez Pittí (born 1971), Panamanian writer, documentary photographer, and computer systems engineer José Luis Rodríguez Vélez (1915–1984), Panamanian musician José Luis Rodríguez Zapatero (born 1960), former Prime Minister of Spain (2004–2011) José Luis Rodríguez (footballer, born 1963), El Puma, former Argentine football striker José Luis Rodríguez (singer) (born 1943), El Puma, Venezuelan singer and actor
Second surname José Luis Deus Rodríguez (born 1977), Spanish former footballer José Luis Exeni Rodríguez (born 1968), Bolivian former chief judge José Luis Lopátegui Rodríguez (1940–2002), Spanish musician, classical guitarist, and professor José Luis Loreto (José Luis Rodríguez Loreto, born 1971), former Spanish football striker José Luis Purcell Rodríguez (1914–1996), Puerto Rican Superior Court judge José Luis Sandoval Rodríguez (born 1968), Mexican professional baseball coach and former player
See also Jose Rodríguez (disambiguation) Luis Rodriguez (disambiguation)