Naringenin 7-O-methyltransferase (, NOMT) (full systematic name S-adenosyl-L-methionine:(2S)-5,7,4'-trihydroxyflavanone 7-O-methyltransferase) is a methyltransferase isolated from rice, which catalyzes the final step in the biosynthesis of sakuranetin from naringenin. The chemical reaction is:
This is a methylation reaction in which the methyl group comes from the cofactor, S-adenosyl methionine (SAM), which becomes S-adenosyl-L-homocysteine (SAH). The enzyme was characterised from Oryza sativa. While the enzyme is not present in healthy rice leaves, it can be induced by treatment with ultraviolet radiation, jasmonic acid and copper chloride.
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