TRNA (guanine10-N2)-dimethyltransferase (, PAB1283, N(2),N(2)-dimethylguanosine tRNA methyltransferase, Trm-G10, PabTrm-G10, PabTrm-m2 2G10 enzyme) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (guanine10-N2)-dimethyltransferase. This enzyme catalyses the following chemical reaction
2 S-adenosyl-L-methionine + guanine10 in tRNA 2 S-adenosyl-L-homocysteine + N2-dimethylguanine10 in tRNA (overall reaction) (1a) S-adenosyl-L-methionine + guanine10 in tRNA S-adenosyl-L-homocysteine + N2-methylguanine10 in tRNA (1b) S-adenosyl-L-methionine + N2-methylguanine10 in tRNA S-adenosyl-L-homocysteine + N2-dimethylguanine10 in tRNA
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