Šimánek (feminine Šimánková) is a Czech surname. Notable people with the surname include:
Jana Šimánková (born 1980), Czech volleyball player Jiří Šimánek (disambiguation), multiple people Leoš Šimánek (1946–2026), Czech traveler Otto Šimánek (1925–1992), Czech actor Robert E. Simanek (1930–2022), American marine
See also Schimanek, Germanized form of the surname