Durham is a surname. Notable people with the surname include:
A Adrian Durham, English football journalist and broadcaster
B Bartlett S. Durham (1824–1859), American physician and the namesake of Durham, North Carolina
C Caden Durham (born 2006), American football player Carl T. Durham (1892–1974) North Carolina politician Chuck Durham (1918-2008), Philanthropist and civil engineer
D David Anthony Durham (born 1969), American novelist Darius Durham (born 1961), American football player
E Edward B. Durham (c. 1870 – c. 1930), American mining engineer and professor
F Florence Margaret Durham (1869–1949), British geneticist
G Geoffrey Durham (born 1949), British comedy magician and actor
H Hugh Durham (born 1937), American college basketball coach
J Jim Durham (1947–2012), American sportscaster Jimmie Durham (1940–2021), American sculptor and poet John Durham (born 1950), American federal prosecutor John Durham (Medal of Honor) (1843–1918), American Civil War soldier and Medal of Honor recipient John Durham (MP) (died 1420), for Middlesex (UK Parliament constituency) John S. Durham (ambassador) (1861–1919), American diplomat Judith Durham (1943–2022), Australian singer, member of The Seekers
L Leon Durham (born 1957), American baseball player
M Martin Durham (1951–2022), British political scientist Michael Durham Scottish courtier and physician Marilyn Durham, author
N Nancy Durham (born c. 1952), Canadian journalist
P Payne Durham (born 2000), American football player Philip Charles Durham (1763–1845), British admiral who fought at the Battle of Trafalgar
R Ray Durham (born 1971), American baseball player Richard Durham (1917-1984), writer and radio producer Rhea Durham (born 1978), American fashion model Ron Durham (1921–2021), Australian rules footballer Ronnia Durham-Balcombe, Saint Vincent and the Grenadines politician
S Susan Durham, neurosurgeon
T Tim Durham (born 1962), businessman and fraudster
W Walter T. Durham (1924–2013), American historian Woody Durham (1941–2018), American radio announcer