23S rRNA (uridine2479-2'-O)-methyltransferase (, AviRb) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (uridine2479-2'-O)-methyltransferase. This enzyme catalyses the following chemical reaction
S-adenosyl-L-methionine + uridine2479 in 23S rRNA S-adenosyl-L-homocysteine + 2'-O-methyluridine2479 in 23S rRNA
Streptomyces viridochromogenes produces the antibiotic avilamycin A which binds to the 50S ribosomal subunit to inhibit protein synthesis.
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