tRNA (cytidine56-2'-O)-methyltransferase (, aTrm56, tRNA ribose 2'-O-methyltransferase aTrm56, PAB1040 (gene)) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (cytidine56-2'-O)-methyltransferase. This enzyme catalyses the following chemical reaction
S-adenosyl-L-methionine + cytidine56 in tRNA S-adenosyl-L-homocysteine + 2'-O-methylcytidine56 in tRNA
The archaeal enzyme specifically catalyses the S-adenosyl-L-methionine dependent 2'-O-ribose methylation of cytidine at position 56 in tRNA transcripts.
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