23S rRNA (uracil747-C5)-methyltransferase (, YbjF, RumB, RNA uridine methyltransferase B) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (uracil747-C5)-methyltransferase. This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + uracil747 in 23S rRNA S-adenosyl-L-homocysteine + 5-methyluracil747 in 23S rRNA

The enzyme specifically methylates uracil747 at C5 in 23S rRNA.

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