Grubbs is a surname. Notable people with the surname include:
Ben Grubbs (1984–), an American football guard Daniel W. Grubbs (1835–1917), an American lawyer, businessman, and politician David Grubbs (1967–), a musician Gary Grubbs (1949–), an American actor Robert H. Grubbs (1942–2021), an American chemist and Nobel laureate Todd Grubbs, an American musician Tom Grubbs (1894–1986), an American baseball pitcher Victor Grubbs, captain of one of the aircraft involved in the Tenerife airport disaster