Lorusso is an Italian surname. Notable people with the surname include:

Benedetto Lorusso (born 1990), Italian footballer Francesco Lorusso (1952–1977), Italian militant Nicholas Lorusso (born 1967), American attorney Salvatore Lorusso (fl. 1970s–2020s), Italian chemist and art historian Silvio Lorusso (born 1985), Italian writer, artist and designer See also Lorusso Industries, a US restaurant foodservice retailer unrelated to Italian cuisine food operators; replaced by Cracker Barrel in 1990 Lo Russo, surname