Lupanine 17-hydroxylase (cytochrome c) (, lupanine dehydrogenase (cytochrome c)) is an enzyme with systematic name lupanine:cytochrome c-oxidoreductase (17-hydroxylating). This enzyme catalyses the following chemical reaction
The oxidation is driven by cytochrome c in its oxidised ferric () form. The enzyme isolated from Pseudomonas putida contains heme C and requires pyrroloquinoline quinone for activity.
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