Abieta-7,13-dien-18-ol hydroxylase (, CYP720B1, PTAO) is an enzyme with systematic name abieta-7,13-dien-18-ol,NADPH:oxygen oxidoreductase (18-hydroxylating). This enzyme catalyses the following chemical reaction
abieta-7,13-dien-18-ol + NADPH + H+ + O2 abieta-7,13-dien-18-al + NADP+ + 2 H2O (overall reaction) (1a) abieta-7,13-dien-18-ol + NADPH + H+ + O2 abieta-7,13-dien-18,18-diol + + NADP+ + H2O: (1b) abieta-7,13-dien-18,18-diol abieta-7,13-dien-18-al + H2O (spontaneous)
Abietadienol hydroxylase is a heme-thiolate protein (P-450).
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