2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming) (, ethylene-forming enzyme, EFE) is an enzyme with systematic name L-arginine,2-oxoglutarate:oxygen oxidoreductase (succinate-forming). This enzyme catalyses the following chemical reaction
2-oxoglutarate + L-arginine + O2 succinate + CO2 + guanidine + (S)-1-pyrroline-5-carboxylate + H2O (overall reaction) (1a) 2-oxoglutarate + L-arginine + O2 succinate + CO2 + L-hydroxyarginine (1b) L-hydroxyarginine guanidine + (S)-1-pyrroline-5-carboxylate + H2O
2-oxoglutarate/L-arginine monooxygenase/decarboxylase catalyses two cycles of the ethylene-forming reaction.
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