Clavaminate synthase (, clavaminate synthase 2, clavaminic acid synthase) is an enzyme with systematic name deoxyamidinoproclavaminate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating). This enzyme catalyses the following chemical reaction
(1) deoxyamidinoproclavaminate + 2-oxoglutarate + O2 amidinoproclavaminate + succinate + CO2 (2) proclavaminate + 2-oxoglutarate + O2 dihydroclavaminate + succinate + CO2 + H2O (3) dihydroclavaminate + 2-oxoglutarate + O2 clavaminate + succinate + CO2 + H2O
Clavaminate synthase contains nonheme iron.
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