Carotenoid-9',10'-cleaving dioxygenase (, BCO2 (gene), beta-carotene 9',10'-monooxygenase (misleading)) is an enzyme with systematic name all-trans-beta-carotene:O2 oxidoreductase (9',10'-cleaving). This enzyme catalyses the following chemical reaction

all-trans-beta-carotene + O2 all-trans-10'-apo-beta-carotenal + beta-ionone

Carotenoid-9',10'-cleaving dioxygenase contains Fe2+.

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