Linoleate 8R-lipoxygenase (, linoleic acid 8R-dioxygenase, 5,8-LDS (bifunctional enzyme), 7,8-LDS (bifunctional enzyme), 5,8-linoleate diol synthase (bifunctional enzyme), 7,8-linoleate diol synthase (bifunctional enzyme), PpoA) is an enzyme with systematic name linoleate:oxygen (8R)-oxidoreductase. This enzyme catalyses the following chemical reaction
linoleate + O2 (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate
Linoleate 8R-lipoxygenase contains heme.
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