Peptide-methionine (S)-S-oxide reductase

Peptide-methionine (S)-S-oxide reductase (, MsrA, methionine sulphoxide reductase A, methionine S-oxide reductase (S-form oxidizing), methionine sulfoxide reductase A, peptide methionine sulfoxide reductase, formerly protein-methionine-S-oxide reductase) is an enzyme with systematic name peptide-L-methionine:thioredoxin-disulfide S-oxidoreductase (L-methionine (S)-S-oxide-forming). This enzyme catalyses the following chemical reaction

(1) peptide-L-methionine + thioredoxin disulfide + H2O peptide-L-methionine (S)-S-oxide + thioredoxin (2) L-methionine + thioredoxin disulfide + H2O L-methionine (S)-S-oxide + thioredoxin

The reaction occurs in the reverse direction.

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